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Compiled by Lauren Underwood, PhD

Published in the journal Pediatrics (from the American Academy of Pediatrics): Technical report:

Committee on Children with Disabilities, 2001. The pediatrician's role in the diagnosis and management of autistic spectrum disorder in children. Pediatrics. 107(5):E85. http://pediatrics.aappublications.org/cgi/contentlfuW107/5/1221 (PDF available free online )

Applications of biomedical interventions for autism:

Kidd, P.M., 2002. Autism, an extreme challenge to integrative medicine. Part 2: Medical Management, Altern Med Rev, 7(6): 472-99

Kidd, P.M., 2002. Autism, an extreme challenge to integrative medicine. Part: 1: The Knowledge Base, Altern Med Rev, 7(4): 292-316.

Whiteley, P., 2001. Autism Unraveled Conference- 'The Biology of Autism Unraveled.' Expert Opin Pharmacother, 2(&): 1191-3.

Correlation between GFCF diet and decrease in ASD symptoms:

Garvey, 1.,2002. Diet in autism and associated disorders, J Fam Health Care, 12(2):24-8.

Knivsberg, A.M., Reichelt, K.L., Hoien, T. and M. Nodland, 2002. A randomized, controlled study of dietary intervention in autistic syndromes, Nutr Neurosci, 5(4): 251-61.

Knivsber, A.M., Reichelt, K.L. and M. Nodland, 2001. Reports on dietary intervention in autistic disorders, Nutr Neurosci, 4( 1 ): 25-37.

Relationship between immune system dysregulation and ASD:

Iyonouchi, H., Sun, S. and N. Itrokazu, 2002. Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder, Neuropsychobiology, 46(2): 76-84

Brudnak, M.A., 2001. Application of genomeceuticals to the molecular and immunological aspects ofautism, Med Hypotheses, 57(2): 186-91.

Iyonouchi, H., Sun, S., and H. Le, 2001. Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression, I Neuroimmunol, 120(1-2): 170-9.

Significance of GSB depletion from resultant thimerosal neurotoxicity:

James, S.J., Slikker HI, W., Melnyk, S. New, E., Pogribna, M, and S. Jernigan, 2005.

Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors, NeruoToxic, (26)1-8.

Association between the presence of abnormal peptides and the ASD population:

Whitely, P. and P. Shattock, 2002. Biochemical aspects in autism spectrum disorders: updating the opioid-excess theory and presenting new opportunities for biomedical intervention, Expert Opin Ther Targets 6(2): 17-83.

Wakefield, A.J., Puleston J.M., Montgomery, S.M., Anthony, A., O'Leary, JJ and S.H. Murch, 2002. Review Article: The concept of entero-colonic encephalopathy, autism and opioid receptor ligands, Aliment Pharmacol Ther, 16(4): 663-74.

Gastrointestinal abnormalities exist within a subset of the ASD population:

Finegold, S.M. et al., 2002. Gastrointestinal microflora studies in late-onset autism, Clin Infect Dis, 1; 35(supp1): S6-S16.

Horvath, K. and J .A. Perman 2002. Autism and .gastrointestinal symptoms, Curr Gastroenterol Rep, 4(3): 251-8.

Horvath, K. and J.A. Perman, 2002. Autistic disorder and gastrointestinal disease, Curr Opin Pedatr, 14(5): 583-7.

Nutritional supplementation suggested for use among ASD population:

Brudnak, M.A., 2002. Probiotics as an adjuvant to detoxification protocols, MedHypotheses, 58 (5): 385-5.

Johnson S., 2001. Micronutrient accumulation and depletion in schizophrenia, epilepsy, autism and Parkinson's disease? Med Hypotheses, 56(5): 641-5

Nutritional supplementation/vitamin therapy used in ASD population:

Page T., 2000. Metabolic approaches to the treatment of autism spectrum disorders, J Autism Dev Disord, 30(5): 463-9

Rimland, B., 1988. Controversies in the treatment of autistic children: vitamin and drug therapy, J Child Neurol, 3 Suppl: S68- 72.

Does heavy metal toxicity playa role in my child's condition?

Bernard, S., Enayati, A., Redwood, L., Roger, H. and T. Binstock, 2001. Autism: a novel form of mercury poisoning, MedHypotheses 56(4): 462-71

Bernard, S., Enayati, A., Roger, H., Binstock, T. and L. Redwood, 2002. The role ofmercury in the pathogenesis of autism, Molecular Psychiatry, 7, S42-S43

Transdermal drug delivery is effective:

Touitou E., 2002. Drug delivery across the skin, Expert Opin Bioi Ther; 2(7): 723-33

Joshi A. and J. Raje, 2002. Sonicated transdennal drug transport, J Control Release 18; 83( 1 ): 13 Casey G., 2002. Physiology of the skin, Nurs Stand May 8-14; 16(34):47-51

Therapeutic uses of injectable methyl B12:

Kumar, S., 2004. Recurrent seizures: and unusual manifestation of vitamin 812 deficiency. Neurollndia, 52(1): 122-123.

Kumar, S., 2004. Vitamin 812 deficiency presenting with an acute reversible extrapyramidal syndrome. Neurollndia, 52(2): 507-509.

Ranganath, L.R., 8aines, M., and N.8. Roberts,2001. Homocysteine and thiol metabolites in vitamin 812 deficiency, Clin Sci, 100(1): 111-116.

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Last modified: 04/24/05